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. 2022 Apr 15;11(3):1217–1229. doi: 10.1007/s40123-022-00504-z

Table 3.

Factors associated with intraocular pressure elevation after a fluocinolone acetonide intravitreal implant (mixed-model analysis)

Fixed effects (reference) Estimate SE P value Lower 95% CI Upper 95% CI
Age (years) −0.05 0.02 0.041 −0.91 −0.01
Sex (male) 0.36 0.47 0.447 −0.57 1.29
IOP before injection (mmHg) 0.58 0.07 < 0.001 0.45 0.71
Dexamethasone implant before FAc injection −1.67 0.64 < 0.001 −2.92 −0.41
Previous IOP-lowering medication (none)
 Single therapy 0.05 0.72 0.944 −1.36 1.46
 Dual therapy 1.04 0.77 0.176 −0.47 2.56
 Triple therapy or more 0.30 1.80 0.867 −3.26 3.86

FAc fluocinolone acetonide, IOP intraocular pressure, SE standard error, 95% CI 95% confidence interval