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. 2022 May 16;8(1):e002301. doi: 10.1136/rmdopen-2022-002301

Table 1.

Disease-modifying antirheumatic drug (DMARD) therapy

AZ
csDMARD bDMARD tsDMARD
Withhold (n) Continue (n) Withhold (n) Continue (n) Withhold (n) Continue (n)
MTX 7 MTX 9 ADA 3 ADA 2 BARI 3 BARI 1
MTX+HCQ 2 MTX+HCQ 3 ETA 2 ETA 1 TOF 4 TOF 3
MTX+SSZ 2 SSZ 1 GOL 1 GOL 2 TOF+MTX 3 TOF+MTX 3
MTX+IXE 0 MTX+IXE 1 IXE 2 IXE 3 UPA 5 UPA 8
MTX+SEC 0 MTX+SEC 1 SEC 2 SEC 3
MTX+TOC 1 MTX+TOC 1 TOC 1 TOC 4
UST 0 UST 2
Total 12 16 11 17 15 15
Pfizer
csDMARD bDMARD tsDMARD
Withhold (n) Continue (n) Withhold (n) Continue (n) Withhold (n) Continue (n)
LEF 1 LEF 1 ADA 4 ADA 5 BARI 4 BARI 4
MTX 7 MTX 8 CTZ CTZ 2 BARI+MTX 1 BARI+MTX 1
MTX+HCQ 4 MTX+HCQ 3 ETA 1 ETA 1 TOF 3 TOF 2
MTX+SSZ 1 MTX+SSZ 3 GOL 0 GOL 1 TOF+MTX 0 TOF+MTX 0
MTX+ETA 0 MTX+ETA 1 GUS 1 GUS 0 UPA 7 UPA 7
MTX+SEC 1 MTX+SEC 0 INF 1 INF 1 UPA+MTX 0 UPA+MTX 1
MTX+TOC 0 MTX+TOC 0 IXE 4 IXE 5
SEC 2 SEC 1
TOC 2 TOC 2
UST 0 UST 1
Total 14 16 15 20 15 15

MTX, methotrexate; HCQ, hydroxychloroquine; SSZ, sulfasalazine; LEF, leflunamide; ADA, adalimumab; CTZ, certolizumab; ETA, etanercept; GOL, golimumab; GUS, guselkumab; INF, infliximab; IXE, ixekizumab; SEC, secukinumab, TOC, tocilizumab, UST, ustekinumab; BARI, baricitinib; TOF, tofacitinib; UPA, upadacitinib.

ADA, adalimumab; BARI, baricitinib; bDMARD, biologic DMARD; csDMARD, conventional synthetic DMARD; CTZ, certolizumab; ETA, etanercept; GOL, golimumab; GUS, guselkumab; HCQ, hydroxychloroquine; INF, infliximab; IXE, ixekizumab; LEF, leflunamide; MTX, methotrexate; SEC, secukinumab; SSZ, sulfasalazine; TOC, tocilizumab; TOF, tofacitinib; tsDMARD, targeted synthetic DMARD; UPA, upadacitinib; UST, ustekinumab.