Table 4.
Dose–response characteristics against HIV-1 infection of oral TAF in BLT hu-mice.
| Pharmacodynamic parameter | Vaginal | Rectal |
|---|---|---|
| ED50 (µmol) | 1.17 | 1.27 |
| ED90 (µmol) | 2.15 | 1.62 |
| m-value ± SEM, R2 | 3.60 ± 0.22, 0.989 | 9.18 ± 1.94, 0.918 |
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