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Schematic outline of the role of (A,B) mast cells in continuous burning pain and vesicles formation in OSF (Adapted and Modified from Pujari and Vidya, 2013), (C) P2X receptors in a continuous burning pain in OSF, (D) chili or spicy food in aggravation of burning pain in OSF. (E) The accumulation of eosinophils in OSF as a consequence of the process of fibrosis and as a result of irritation by areca nut byproducts.
