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. 2022 May 4;13:819807. doi: 10.3389/fimmu.2022.819807

Figure 1.

Figure 1

The graphical abstract depicts the tumor microenvironment (TME) in gastrointestinal cancer, outlines the methodologies for deciphering TME compartments, and elucidates the existing TME-relevant biomarkers in the prognostic, chemotherapeutic, and immunotherapeutic settings. Methods for TME assessment comprised the immunohistochemistry (IHC), the computational toolbox for NGS-based analyses, and radiomics detections. NK cell, natural killer cell; Treg cell, regulatory T cells; DC, dendritic cell; TAM, tumor-associated macrophages; CAF, cancer-associated fibroblasts; MDSC, myeloid-derived suppressor cell; NGS, next-generation sequencing.