Table 1.
The implementation and comparison of biomarkers based on TME evaluation.
| Methodology | Cancer | Biomarkers | Prognosis | Chemotherapy response | Immunotherapy response |
|---|---|---|---|---|---|
| IHC | GC | GC-SVM classifier | Yes | Yes | |
| GC | Immunoscore/TNM-Immune | Yes | |||
| GC | ISGC | Yes | |||
| CRC | CRS | Yes | |||
| bulk-seq | GC | Immunoscore | Yes | Yes | |
| GC | TMEscore | Yes | Yes | ||
| GC | PNM score system | Yes | Yes | Yes | |
| GC/CRC | IO-score | Yes | Yes | ||
| CRC | CSS sets | Yes | Yes | ||
| CRC | TMRS | Yes | Yes | ||
| CRC | pIRS | Yes | |||
| Pan-cancer | T cell-inflamed GEP score | Yes | |||
| Pan-cancer | Immunophenoscore | Yes | |||
| Pan-cancer | TIDE | Yes | |||
| Radiomics | GC | RIS | Yes | ||
TME, tumor microenvironment; IHC, immunohistochemistry; GEP, gene expression profile.