Table 3.
Superficial and deep macular and radial peripapillary capillary vessel density, foveal avascular zone, and optic nerve head parameters of caffeine group at baseline and 1 h after caffeine intake
| Caffeine Group baseline (n=60) | 1 h After Caffeine Intake (n=60) | P | |
|---|---|---|---|
| Superficial Macular Vessel Density (VD)(%) | |||
| wiVD | 53.00 (52.05-53.97) | 51.10 (49.70-52.67) | <0.001† |
| Sup hemi VD | 52.90 (52.00-53.77) | 51.20 (49.55-52.30) | <0.001† |
| Inf hemi VD | 53.30 (52.20-54.20) | 51.05 (49.52-52.62) | <0.001† |
| Fovea | 22.14±6.78 | 20.07±6.66 | <0.001* |
| Parafovea | 55.95 (54.67-57.30) | 53.20 (50.80-55.35) | <0.001† |
| Para sup hemi | 56.10 (54.35-57.22) | 53.05 (51.22-55.47) | <0.001† |
| Para inf hemi | 56.15 (54.40-57.00) | 53.40 (50.42-55.25) | <0.001† |
| Para superior | 56.57±2.63 | 53.30±4.21 | <0.001* |
| Para nasal | 55.10 (53.70-56.57) | 52.65 (51.05-54.62) | <0.001† |
| Para inferior | 56.50 (55.50-58.00) | 54.00 (49.52-55.87) | <0.001† |
| Para temporal | 55.36±2.85 | 52.20±3.84 | <0.001* |
| Perifovea | 53.90 (52.70-54.67) | 51.95 (50.35-53.47) | <0.001† |
| Peri sup hemi | 53.80 (52.80-54.67) | 51.70 (50.32-53.17) | <0.001† |
| Peri inf hemi | 53.86±2.44 | 51.43±3.09 | <0.001* |
| Peri superior | 53.95 (52.30-55.25) | 52.10 (49.92-53.37 | <0.001† |
| Peri nasal | 57.65 (56.22-58.60) | 55.60 (53.72-57.10) | <0.001† |
| Peri inferior | 54.30 (52.60-55.62) | 52.10 (49.75-53.87) | <0.001† |
| Peri temporal | 50.40 (49.25-51.65) | 47.65 (45.70-49.67) | <0.001† |
| Deep Macular Vessel Density (VD)(%) | |||
| wiVD | 58.44±3.99 | 54.07±5.03 | <0.001* |
| Sup hemi VD | 58.42±3.83 | 53.82±5.05 | <0.001* |
| Inf hemi VD | 59.80 (56.30-61.55) | 55.20 (49.22-58.82) | <0.001† |
| Fovea | 41.43±7.72 | 38.63±6.86 | <0.001* |
| Parafovea | 60.95 (58.55-62.07) | 58.55 (55.72-60.60) | <0.001† |
| Para sup hemi | 60.72±2.40 | 57.85±3.22 | <0.001* |
| Para inf hemi | 61.30 (58.82-62.37) | 57.90 (54.87-59.90) | <0.001† |
| Para superior | 60.24±2.73 | 57.03±3.57 | <0.001* |
| Para nasal | 62.35 (60.42-63.57) | 59.30 (56.70-60.87) | <0.001† |
| Para inferior | 60.15 (58.02-61.60) | 56.25 (52.77-59.40) | <0.001† |
| Para temporal | 61.60 (59.82-62.75) | 59.35 (56.92-60.67) | <0.001† |
| Perifovea | 61.55 (57.95-63.10) | 56.70 (51.30-59.85) | <0.001† |
| Peri sup hemi | 60.24±4.11 | 55.45±5.46 | <0.001* |
| Peri inf hemi | 61.50 (58.35-63.70) | 56.30 (50.57-60.15) | <0.001† |
| Peri superior | 60.15 (57.92-63.27) | 55.15 (50.42-59.20) | <0.001† |
| Peri nasal | 60.55 (57.50-63.37) | 54.95 (49.35-58.97) | <0.001† |
| Peri inferior | 62.20 (58.77-64.65) | 56.75 (50.72-60.67) | <0.001† |
| Peri temporal | 62.40 (59.67-63.20) | 58.25 (54.82-60.35) | <0.001† |
| Radial peripapillary capillary vessel density (RPC VD) | |||
| wpVD | 50.48±2.06 | 48.99±2.12 | <0.001* |
| iVD | 53.32±3.74 | 49.82±4.34 | <0.001* |
| ppVD average | 53.00 (52.10-54.15) | 51.15 (49.60-52.75 | <0.001† |
| ppVD sup hemi | 53.33±2.13 | 51.19±2.34 | <0.001* |
| ppVD inf hemi | 53.26±2.40 | 50.84±2.53 | <0.001* |
| ppVD superior | 53.00 (51.25-55.00) | 50.00 (48.00-53.00) | <0.001† |
| ppVD nasal | 50.00 (48.25-52.00) | 49.00 (47.00-50.00) | <0.001† |
| ppVD inferior | 55.00 (53.25-57.00) | 51.00 (50.00-54.00) | <0.001† |
| ppVD temporal | 55.45±3.11 | 53.43±2.90 | <0.001* |
| Foveal avscular zone (FAZ) parameters | |||
| FAZ area (mm2) | 0.27±0.09 | 0.27±0.09 | 0.724* |
| FAZ perimeter (mm) | 2.06 (1.70-2.23) | 2.08 (1.70-2.23 | 0.818† |
| FD-300 | 57.33±3.52 | 54.61±4.04 | <0.001* |
wiVD: whole image vessel density, para: parafovea, peri: perifovea, sup hemi: superior hemifield, inf hemi: inferior hemifield, wpVD: whole papillary vessel density, İVD: inside disk vessel density, ppVD: peripapillary vessel density, FD: FAZ density. *student t-test was used for comparison, †Mann-Whitney U test used for comparison