Table 4.
Superficial and deep macular and radial peripapillary capillary vessel density, foveal avascular zone, and optic nerve head parameters of control group at baseline and 1 h after placebo intake
| Control Group baseline (n=60) | 1 h After Placebo Intake (n=60) | P | |
|---|---|---|---|
| Superficial Macular Vessel Density (VD)(%) | |||
| wiVD | 52.75 (51.02-53.90) | 52.10 (50.90-54.05) | 0.199† |
| Sup hemi VD | 53.20 (52.02-54.60) | 53.25 (51.52-54.77) | 0.310† |
| Inf hemi VD | 53.20 (51.22-54.55) | 52.80 (51.17-54.20) | 0.189† |
| Fovea | 23.24±7.05 | 22.82±7.43 | 0.276* |
| Parafovea | 56.00 (54.65-58.02) | 56.05 (54.22-57.50) | 0.303† |
| Para sup hemi | 56.45 (54.52-58.37) | 55.85 (54.37-57.97) | 0.416† |
| Para inf hemi | 56.00 (54.47-58.02) | 56.50 (54.30-57.95) | 0.505† |
| Para superior | 56.80 (54.90-59.30) | 56.35 (54.75-58.07) | 0.310† |
| Para nasal | 55.40 (53.02-57.60) | 55.80 (52.70-57.97) | 0.971† |
| Para inferior | 56.80 (55.00-58.77) | 56.75 (54.02-58.62) | 0.401† |
| Para temporal | 56.05 (53.82-57.82) | 55.70 (54.12-57.20) | 0.347† |
| Perifovea | 53.72 (51.94-54.89) | 53.17 (51.62-55.09) | 0.168† |
| Peri sup hemi | 53.40 (51.70-55.15) | 53.05 (51.40-55.17) | 0.381† |
| Peri inf hemi | 53.92±2.58 | 53.16±3.50 | 0.107* |
| Peri superior | 53.70 (52.45-55.15) | 53.70 (52.02-56.42) | 0.616† |
| Peri nasal | 57.74±2.56 | 57.21±3.02 | 0.212* |
| Peri inferior | 54.37±2.78 | 53.64±3.35 | 0.123* |
| Peri temporal | 50.60 (48.82-52.70) | 50.80 (48.70-52.47) | 0.211† |
| Deep Macular Vessel Density (VD)(%) | |||
| wiVD | 59.30 (55.85-62.75) | 60.70 (56.92-62.95) | 0.567† |
| Sup hemi VD | 58.05 (53.42-60.65) | 58.60 (54.70-61.10) | 0.363† |
| Inf hemi VD | 59.90 (55.52-63.47) | 61.20 (57.77-63.30) | 0.363† |
| Fovea | 40.70 (35.62-47.15) | 42.45 (36.15-45.97) | 0.777† |
| Parafovea | 61.10 (57.82-62.97) | 61.35 (59.80-63.45) | 0.101† |
| Para sup hemi | 61.15 (57.50-63.05) | 61.25 (59.65-63.50) | 0.094† |
| Para inf hemi | 60.90 (57.70-63.40) | 61.60 (59.35-63.50) | 0.085† |
| Para superior | 60.25 (57.02-62.30) | 61.30 (58.62-62.87) | 0.172† |
| Para nasal | 62.10 (58.75-63.77) | 62.45 (60.72-64.70) | 0.074† |
| Para inferior | 58.45 (55.40-61.52) | 59.55 (57.10-61.67) | 0.086† |
| Para temporal | 61.90 (58.80-63.50) | 62.30 (60.10-64.07) | 0.154† |
| Perifovea | 61.10 (57.42-64.97) | 62.90 (59.37-65.25) | 0.219† |
| Peri sup hemi | 59.45 (54.55-62.47) | 60.50 (57.30-63.05) | 0.208† |
| Peri inf hemi | 61.85 (56.67-65.60) | 63.80 (59.65-65.47) | 0.367† |
| Peri superior | 59.00 (54.75-62.67) | 60.45 (57.90-63.30) | 0.291† |
| Peri nasal | 60.75 (54.62-64.27) | 60.65 (57.47-64.07) | 0.476† |
| Peri inferior | 62.65 (57.37-66.35) | 64.05 (61.00-65.70) | 0.516† |
| Peri temporal | 61.60 (58.25-64.85) | 62.90 (60.62-65.50) | 0.062† |
| Radial peripapillary capillary vessel density (RPC VD) | |||
| wpVD | 50.90 (49.45-51.97) | 51.00 (49.70-52.10) | 0.901† |
| iVD | 53.97±4.09 | 53.34±4.12 | 0.120* |
| ppVD average | 53.85 (52.25-55.45) | 54.55 (52.50-55.87) | 0.188† |
| ppVD sup hemi | 53.22±2.59 | 53.64±2.97 | 0.192* |
| ppVD inf hemi | 54.10 (51.62-55.25) | 54.45 (51.87-56.07) | 0.524† |
| ppVD superior | 53.00 (51.00-56.00) | 54.00 (51.00-57.00) | 0.053† |
| ppVD nasal | 51.00 (48.00-52.00) | 51.00 (48.25-53.00) | 0.615† |
| ppVD inferior | 54.00 (50.25-57.00) | 55.00 (52.00-58.00) | 0.050† |
| ppVD temporal | 55.00 (53.00-57.00) | 55.00 (53.25-57.00) | 0.565† |
| Foveal avscular zone (FAZ) parameters | |||
| FAZ area (mm2) | 0.30±1.2 | 0.30±1.2 | 0.777* |
| FAZ perimeter (mm) | 2.11±0.43 | 2.12±0.44 | 0.365* |
| FD-300 | 56.48 (54.10-59.77) | 56.66 (54.07-59.15) | 0.860† |
wiVD: whole image vessel density, para: parafovea, peri: perifovea, sup hemi: superior hemifield, inf hemi: inferior hemifield, wpVD: whole papillary vessel density, İVD: inside disk vessel density, ppVD: peripapillary vessel density, FD: FAZ density. *Student t-test was used for comparison, †Mann-Whitney U test used for comparisons