Table 2.
Characteristics of patients with bone and joint infections subgrouped according to age into infants (≤ 3 months), young children (>3–60 months), older children (>60 months).
| OM | SA | OM + SA | P -value* | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Infants |
Young children |
Older children |
Infants |
Young children |
Older children |
Infants |
Young children |
Older children |
Infant groups |
Young children groups |
Older children groups |
|
| Nr. of patients (%) | 6 (3) | 74a (36) | 123c (61) | 3 (2) | 101a, b (64) | 54c (34) | 1 (5) | 6b (32) | 12 (63) | 0.44 | <0.0001a 0.011b | <0.0001 c |
| Median age in months (IQR) | 2 (1–2) | 23 (13–39) | 124 (89–153) | 1 (1–1.5) | 17 (12–30) | 117 (80–144) | 1.6 | 18 (15–24) | 116 (87–151) | 0.12 | 0.28 | 0.14 |
| Females (%) | 5 (83) | 28 (38) | 53 (43) | 3 (100) | 45 (45) | 22 (41) | 0 | 4 (67) | 2 (17) | 0.26 | 0.32 | 0.21 |
| Patients with systemic infections (%) | 0 | 9 (12) | 25 (20) | 0 | 14 (14) | 13 (24) | 0 | 1 (17) | 4 (33) | - | 0.78 | 0.45 |
| Patients admitted to PICU (%) | 1 (17) | 7 (9) | 13 (9) | 0 | 6 (6) | 4 (7) | 0 | 0 | 4 (33) | >0.99 | 0.62 | 0.051 |
| Median days in PICU (IQR) | 7 | 2 (1–6) | 3 (2–8) | 0 | 3 (3–7) | 3 (1–5) | 0 | 0 | 9 (4–10) | - | 0.41 | 0.39 |
| Median days of hospitalization (IQR) | 13 (9–33) | 9 (5–14) | 11 (7–17) | 7 (4–10) | 7 (5–11) | 10 (6–15) | 6 | 18 (11–22) | 21 (10–31) | 0.36 | 0.030 | 0.031 |
| Days of IV antibiotic therapy (IQR) | 8 (6–21) | 9a (5–14) | 12 (9–20) | 8 (5–14) | 5a (4–6) | 10 (5–14) | - | 14 | 15 (10–20) | 0.80 | 0.0008 a | 0.21 |
| S.aureus | 3 | 25a | 64 | - | 10a | 29 | - | 2 | 8 | >0.999 | 0.0003 a | 0.45 |
| GAS | - | 6 | 12 | - | 15 | 9 | - | - | 3 | - | 0.35 | 0.14 |
| K.kingae | - | - | - | - | 22 | - | - | - | - | - | <0.0001 | - |
| S. pneumoniae | - | 2 | 1 | - | 10 | 3 | - | - | - | - | 0.16 | 0.13 |
| N.meningitidis | - | 1 | - | - | 3 | 1 | - | - | - | - | 0.682 | 0.339 |
| Salmonella | - | - | 1 | - | 1 | - | - | - | - | - | >0.999 | >0.999 |
| Other bacteria | 1 | 2 | 4 | 2 | 4 | 1 | - | 2 | - | 0.458 | 0.053 | >0.999 |
*
P-values were calculated by comparing the OM-, SA- and OM + SA groups with each other. Kruskal-Wallis or Mann-Whitney test (continuous data) and Fisher's Exact tests (categorical data) were used, as appropriate. α was adjusted by Bonferroni correction.
a, b, c
Medians or total numbers on the same row are significantly different (P ≤ 0.05) when compared between groups.
Bold values indicate statistically significant (p-value < 0.05).