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Staining evaluations of the therapeutic effect of FSPOH on papain-induced OA. (A) and (B) Representative images of TUNEL immunofluorescence and Collagen2 and Aggrecan immunohistochemistry of each group after treatment for 3 and 6 weeks. Scale bar is 200 μm. (C), (D), (E) Quantitative analysis of the percentage of TUNEL and Collagen2 and Aggrecan positive cells. ∗P < 0.05; ∗∗P < 0.01; ∗∗∗P < 0.001.
