Table 2.
Currently identified major ECM types in adult pancreatic islets. Species-specific information is included in the table when appropriate with literature references.
| Peri-Islet ECM | Vascular Intra-Islet ECM | |
|---|---|---|
| Peri-islet BM | Peri-Islet IM | Vascular BM (mice) and Vascular BM + Peri-islet BM (humans) |
| Collagen-IV [α1 & α2 in mouse islets (20)] | Collagen-I, -III, -VI (21) | Collagen-III, -IV, -VI (16, 21, 22) |
| Laminins [LM-211, -411 in mouse islets (21); LM-511, -521 in human islets (23)] | Fibrillin-2 (21) | Laminins (LM-211, -221, -411, -421, -511, -521 in human & mouse islets) (24–26) |
| Tenascins (21) | ||
| Heparan Sulfate Proglycans (i.e., Perlecan) (21) | Matrilin-2 (24) | |
| Chondroitin (21) | ||
| Dermatan Sulfate Proteoglycans (21) | ||
| Nidogen-1, -2 (21) | Vitronectin (21) | |
| Fibronectin (27) | Fibronectin (21) | |