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. 2022 May 4;10:899760. doi: 10.3389/fbioe.2022.899760

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Copyright © 2022 Tian, Wu, Wu, Cui, Ren, Wang, Wang and Peng.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Chitosan-coated PHBV/CaSH scaffold was used to improve the bone repair (Ye et al., 2018b). (A) Preparation process for the PHBV/CaSH/CS scaffold. (B) Surface morphology and mechanical properties of the PHBV, PHBV/CaSH and PHBV/CaSH/CS scaffolds. (C) H&E staining results at 4 and 12 weeks. (D) Masson’s trichrome staining performed at 4 and 12 weeks. 3D, three-dimensional; CS, chitosan; DI, deionized; H&E, hematoxylin and eosin; PHBV/CaSH, poly (3-hydroxybutyrate-co-3-hydroxyvalerate)/calcium sulfate hemihydrate.