TABLE 2.

Linear regression models for the association with log‐IgG(S) after the second dose of BNT162b2 vaccine

	Main cohort (linear mixed effect model)		Confirmatory cohort (linear model)
	Beta (SE)	p‐value	Beta (SE)	p‐value
History of SARS‐Cov‐2 infection
COV‐No	7.31 (0.21)	<0.0001	8.30 (0.47)	<0.0001
COV‐Yes	9.21 (0.17)	<0.0001	9.20 (0.72)	<0.0001
Time since second dose of vaccine (months)
Among COV‐No subjects	−0.35 (0.02)	<0.0001	−0.49 (0.07)	<0.0001
Among COV‐Yes subjects	−0.29 (0.02)	<0.0001	−0.31 (0.12)	0.011
Time since second dose of vaccine × Covid‐19 status	Interaction p‐value = 0.051		Interaction p‐value = 0.20