TABLE 4.

Antifungals minimum inhibitory concertation (MICs) for Candida auris isolates from COVID‐19 patients

Antifungals	No. of isolates	MICs in Range (mg/L)	Geometric Mean	MIC50	MIC90	No. of C. auris isolates with MICs (mg/L)
						0.015	0.03	0.06	0.125	0.25	0.5	0.75	1	2	4	8	16	32	64	128	256	512
Amphotericin B	41	0.125–8	1.29	1	4	0	0	0	1	1	8	5	7	9	9	1	0	0	0	0	0	0
Caspofungin	39	0.125–8	0.597	0.5	2	0	0	0	5	7	8	0	14	3	1	1	0	0	0	0	0	0
Micafungin	27	0.03–8	0.207	0.25	1	0	1	4	8	8	3	0	2	0	0	1	0	0	0	0	0	0
Anidulafungin	38	0.06–8	0.431	0.5	1	0	0	2	5	8	12	0	9	0	1	1	0	0	0	0	0	0
Fluconazole	41	2–512	92.83	256	256	0	0	0	0	0	0	0	0	2	0	2	4	5	4	1	19	4
Voriconazole	41	0.03–8	0.56	1	2	0	3	1	5	6	4	0	10	9	2	1	0	0	0	0	0	0
Isavuconazole	32	0.03–1	0.15	0.125	0.5	0	3	6	11	5	6	0	1	0	0	0	0	0	0	0	0	0
Posaconazole	35	0.015–8	0.095	0.125	0.25	1	9	5	14	3	2	0	0	0	1	0	0	0	0	0	0	0
Itraconazole	23	0.06–16	0.38	0.25	1	0	0	2	2	9	6	0	1	2	0	0	1	0	0	0	0	0
5‐Flucytosine	16	0.25‐–64	6.44	8	64	0	0	0	0	4	0	0	2	0	0	2	1	1	6	0	0	0

The data provided in the table were extracted from 5 studies. ¹³ , ¹⁴ , ²² , ²³ , ²⁴

Abbreviations: MIC, minimum inhibitory concentration.

MIC₅₀: MIC at which 50% of the tested isolates are inhibited.

MIC₉₀: MIC at which 90% of the tested isolates are inhibited.