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. 2021 Jun 28;42(5):528–583. doi: 10.1210/endrev/bnab021

Figure 2.

Figure 2.

Epigenetic modifications occurring in the β cell. Environmental factors and/or genetics can contribute to epigenetic alterations in the β cell, thereby modifying expression of genes involved in β-cell function and survival. Epigenetic alterations include DNA methylation, histone modifications, and non-coding RNAs.