Figure 2.

High TRIP13 expression promotes cell proliferation and migration as well as induces resistance to nedaplatin in KYSE150 cells. (a) The TRIP13 plasmids were transfected successfully into KYSE150 cells examined by Western blot. (b) Colony formation assay of KYSE150 with TRIP13 plasmids transfection. (c) The cell proliferation of KYSE150 was increased after TRIP13 plasmids transfection tested by colony formation assay. (d) With high expression of TRIP13 induced by TRIP13 plasmids, the cell proliferation of KYSE150 cells was increased tested by MTS assay. (e) With the effect of nedaplatin, the proliferation promoting rate in KYSE150 cells was enhanced. (f) Transwell assay of KYSE150 cells with TRIP13 plasmids transfection. (g) The cell migration was increased in KYSE150 cells after TRIP13 plasmids transfection. (h) With the effect of nedaplatin, the migration promoting rate in KYSE150 cells was enhanced.