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. 2022 May 10;2022:7295458. doi: 10.1155/2022/7295458

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Copyright © 2022 Lin-Ting Zhang et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Low TRIP13 expression inhibits cell proliferation and migration as well as weakens resistance to nedaplatin in KYSE30 cells. (a) The siTRIP13-2 and siTRIP13-3 were transfected successfully into KYSE30 cells examined by Western blot. (b) Colony formation assay of KYSE30 with siTRIP13-2 and siTRIP13-3 transfection. (c) The cell proliferation of KYSE30 was decreased after siTRIP13-2 and siTRIP13-3 transfection tested by colony formation assay. (d) The cell proliferation of KYSE30 cells was decreased after siTRIP13-2 transfection tested by MTS assay. (e) With the effect of nedaplatin, the proliferation inhibition rate of KYSE30 cells was enhanced. (f) Transwell assay of KYSE30 cells with siTRIP13-2 transfection. (g) The cell migration was decreased in KYSE30 cells after siTRIP13-2 transfection. (h) With the effect of nedaplatin, the migration inhibition rate of KYSE30 cells was enhanced.