Table. Proportion of US Adults Eligible for Prediabetes and Diabetes Screening According to USPSTF and ADA Guidelines, Overall and Among Those With Prediabetes or Undiagnosed Diabetes, NHANES 2015-2020a.
| Unweighted No. eligible for screening | Weighted percentage eligible for screening (95% CI) | |
|---|---|---|
| Overall (N = 4480) | ||
| USPSTF 2015 guidelines | 1640 | 36.3 (34.1-38.5) |
| USPSTF 2021 guidelines | 1939 | 43.0 (40.5-45.6) |
| ADA 2003 guidelines | 3657 | 76.7 (73.8-79.3) |
| ADA 2022 guidelines | 3898 | 82.9 (80.1-85.3) |
| Adults with prediabetes (n = 1961)b | ||
| USPSTF 2015 guidelines | 933 | 50.1 (47.3-52.9) |
| USPSTF 2021 guidelines | 1046 | 56.2 (53.3-59.0) |
| ADA 2003 guidelines | 1823 | 89.4 (85.0-92.5) |
| ADA 2022 guidelines | 1882 | 93.7 (90.3-96.0) |
| Adults with undiagnosed diabetes (n = 164)c | ||
| USPSTF 2015 guidelines | 96 | 58.7 (44.5-71.5) |
| USPSTF 2021 guidelines | 109 | 67.8 (53.1-79.7) |
| ADA 2003 guidelines | 158 | 97.6 (93.0-99.2) |
| ADA 2022 guidelines | 161 | 99.1 (95.9-99.8) |
| Adults with confirmed undiagnosed diabetes (n = 52)d | ||
| USPSTF 2015 guidelines | 29 | 50.9 (32.8-68.7) |
| USPSTF 2021 guidelines | 37 | 73.2 (53.9-86.5) |
| ADA 2003 guidelines | 51 | 98.3 (88.1-99.8) |
| ADA 2022 guidelines | 52 | 100 |
Abbreviations: ADA, American Diabetes Association; BMI, body mass index (calculated as weight in kilograms divided by height in meters squared); HbA1c, hemoglobin A1c; NHANES, National Health and Nutrition Examination Survey; USPSTF, US Preventive Services Task Force.
Screening criteria were defined as age 40 to 70 years and BMI of 25 or greater for USPTF 2015 guidelines; age 35 to 70 years and BMI of 25 or greater for USPTF 2021 guidelines; age 45 years or older or BMI of 25 or greater and 1 additional risk factor for ADA 2003 guidelines; and age 35 years or older or BMI of 25 or greater and 1 additional risk factor for ADA 2022 guidelines.
Prediabetes was defined as HbA1c of 5.7% to 6.4% or fasting plasma glucose level of 100 to 125 mg/dL.
Undiagnosed diabetes was defined as HbA1c of 6.5% or greater or fasting plasma glucose level of 126 mg/dL or greater.
Confirmed undiagnosed diabetes was defined as HbA1c of 6.5% or greater and fasting plasma glucose level of 126 mg/dL or greater.