. Author manuscript; available in PMC: 2022 May 18.

Published in final edited form as: Osteoarthritis Cartilage. 2019 Feb 28;27(6):863–870. doi: 10.1016/j.joca.2019.01.018

Table 4:

Comparison of rate of change of cartilage, meniscus and bone marrow edema pattern WORMS sum score over 96-months

Rate of change of WORMS over 96 months	Stable overweight vs. >5% weight loss	P-value
	Adjusted mean difference of rate of change/year [95% CI]

Cartilage lesions
Global knee	0.10 [−0.06, 0.25]	0.34
PAT	0.02 [0.00, 0.04]	0.46
T	0.00 [−0.06, 0.05]	0.93
MT	0.02 [−0.3, 0.04]	0.42
LT	0.02 [−0.03, 0.04]	0.46
MF	0.03 [−0.03, 0.04]	0.28
LF	0.01 [−0.03, 0.04]	0.74
Meniscus lesions
Meniscus lesions sum	0.08 [0.02, 0.21]	0.021
Medial meniscus lesions sum	0.06 [0.02, 0.09]	0.005
Lateral meniscus lesions sum	0.02 [0.00, 0.08]	0.86
BMEP lesions
BMEP lesions sum	0.02 [0.00, 0.08]	0.85

LF, lateral femur; LT, lateral tibia; MF, medial femur; MT, medial tibia; PAT, patella

The adjusted mean differences of associations of the rate of change of WORMS between the weight loss group and stable weight group over 96 months were assessed using multivariable regression models adjusting for age, sex, baseline BMI and baseline KL score. Significant results (P < 0.05) are bolded.