Table 1.
Demographic and clinical characteristics of cohort participants according to year of first visit
| Variables | 2004–2006 | 2007–2009 | 2010–2012 | 2013–2015 | Total | |
|---|---|---|---|---|---|---|
| N (%) | N (%) | N (%) | N (%) | N (%) | p-value | |
| Age | < 0.001 | |||||
| Median (IQR) | 37 (29.0–43.0) | 35 (28.0–42.8) | 34 (28.0–43.0) | 33 (27.0–42.0) | 35 (28.0–43.0) | < 0.001† |
| 18–24 | 77 (9.6) | 125 (11.8) | 147 (13.8) | 138 (14.6) | 4687 (12.6) | |
| 25–34 | 273 (33.9) | 394 (37.1) | 388 (36.3) | 372 (39.5) | 1427 (36.8) | |
| 35–49 | 365 (45.3) | 437 (41.1) | 402 (37.6) | 323 (34.3) | 1527 (39.4) | |
| 50 or more | 91 (11.3) | 106 (10.0) | 132 (12.3) | 109 (11.6) | 438 (11.3) | |
| Ethnicity/skin color | < 0.0001 | |||||
| White | 499 (61.9) | 483 (45.5) | 430 (40.2) | 344 (36.5) | 1756 (45.3) | |
| Black | 122 (15.1) | 202 (19.0) | 262 (24.5) | 189 (20.1) | 775 (20.0) | |
| Brown | 184 (22.8) | 369 (34.7) | 352 (32.9) | 394 (41.8) | 1299 (33.5) | |
| Missing | 1 (0.1) | 8 (0.8) | 25 (2.3) | 15 (1.6) | 49 (1.3) | |
| Years of education | < 0.0001 | |||||
| ≤ 5 | 213 (26.4) | 294 (27.7) | 330 (30.9) | 227 (24.1) | 1064 (27.4) | |
| 6–9 | 192 (23.8) | 226 (21.3) | 182 (17.0) | 112 (11.9) | 712 (18.4) | |
| ≥ 10 | 397 (49.3) | 539 (50.8) | 537 (50.2) | 584 (62.0) | 2057 (53.0) | |
| Missing | 4 (0.5) | 3 (0.3) | 20 (1.9) | 19 (2.0) | 46 (1.2) | |
| Gender/sexual preference | < 0.0001 | |||||
| Cis-W | 240 (29.8) | 346 (32.6) | 322 (30.1) | 213 (22.6) | 1121 (28.9) | |
| Trans-W | 5 (0.6) | 34 (3.2) | 29 (2.7) | 102 (10.8) | 170 (4.4) | |
| MSM | 293 (36.4) | 362 (34.1) | 384 (45.9) | 364 (38.6) | 1403 (36.3) | |
| MSW | 211 (26.2) | 264 (24.9) | 226 (21.1) | 124 (13.2) | 825 (21.3) | |
| Missing | 57 (7.1) | 56 (5.3) | 108 (10.1) | 139 (14.8) | 360 (9.3 | |
| ART-naïve before first visit | < 0.0001 | |||||
| No | 230 (28.5) | 165 (15.5) | 216 (20.2) | 248 (26.3) | 859 (22.1) | |
| Yes | 576 (71.5) | 897 (84.5) | 853 (79.8) | 694 (73.7) | 3020 (77.9) | |
| CD4 count (cells/µL)1 | 0.31 | |||||
| ≤ 50 | 97 (12.0) | 144 (13.6) | 153 (14.3) | 120 (12.7) | 514 (13.3) | |
| 51–200 | 164 (20.3) | 217 (20.4) | 213 (19.9) | 177 (18.8) | 771 (19.9) | |
| 201–350 | 155 (19.2) | 184 (17.3) | 180 (16.8) | 166 (17.6) | 685 (17.7) | |
| > 350 | 328 (40.7) | 439 (41.3) | 461 (43.1) | 430 (45.6) | 1658 (42.7) | |
| Missing | 62 (7.7) | 78 (7.3) | 62 (5.8) | 49 (5.2) | 251 (6.5) | |
| Viral load (copies/mL)1 | < 0.0001 | |||||
| < 400 | 112 (13.9) | 173 (16.3) | 222 (20.8) | 209 (22.2) | 716 (18.5) | |
| 400–999 | 25 (3.1) | 22 (2.1) | 43 (4.0) | 24 (2.5) | 114 (2.9) | |
| ≥ 1.000 | 508 (63.0) | 693 (65.3) | 712 (66.6) | 641 (68.0) | 2554 (65.8) | |
| Missing | 161 (20.0) | 174 (16.4) | 92 (8.6) | 68 (7.2) | 495 (12.8) | |
| Prior AIDS-defining illness2 | < 0.0001 | |||||
| No | 641 (79.5) | 763 (71.8) | 758 (70.9) | 712 (75.6) | 2874 (74.1) | |
| Yes | 165 (20.5) | 299 (28.2) | 311 (29.1) | 230 (24.4) | 1005 (25.9) | |
| Total | 806 | 1062 | 1069 | 942 | 3879 | |
INI cohort, 2004–2015 (N = 3879)
IQR Interquartile range
†p-value regarding the Brown-Mood test for median difference
1CD4 count and viral load were measured at first visit
2Prior AIDS-defining illness was defined using a window of 180 days before up to 30 days after first visit