Table 4.
Variables | Unadjusted model HR (95% CI) |
p-value | Adjusted model HR (95% CI) |
p-value |
---|---|---|---|---|
Age | ||||
10 year increase | 1.70 (1.44–2.01) | < 0.0001 | 1.57 (1.25–1.97) | < 0.001 |
Ethnicity/skin color | ||||
White | 1.00 | – | 1.00 | – |
Black | 1.41 (0.85–2.33) | 0.18 | 1.64 (0.88–3.04) | 0.12 |
Brown | 0.75 (0.45–1.27) | 0.29 | 0.93 (0.51–1.72) | 0.83 |
Years of education | ||||
≤ 5 | 2.17 (1.35–3.48) | < 0.01 | 1.91 (1.03–3.53) | 0.04 |
6 a 9 | 1.30 (0.73–2.39) | 0.40 | 1.04 (0.47–2.26) | 0.93 |
≥ 10 | 1.00 | – | 1.00 | – |
Year of first visit | ||||
2004–2006 | 3.93 (1.87–8.26) | < 0.001 | 4.50 (1.80–11.23) | < 0.01 |
2007–2009 | 2.82 (1.33–5.95) | < 0.01 | 2.59 (1.03–6.51) | 0.04 |
2010–2012 | 1.84 (0.83–4.08) | 0.13 | 1.67 (0.64–4.37) | 0.30 |
2013–2015 | 1.00 | – | 1.00 | - |
Gender/sexual preference | ||||
Cis-W | 1.00 | – | 1.00 | – |
Trans-W | 1.05 (0.24–4.61) | 0.95 | 2.84 (0.63–12.82) | 0.17 |
MSM | 1.42 (0.74–2.72) | 0.29 | 2.07 (1.01–4.24) | 0.05 |
MSW | 2.26 (1.17–4.38) | 0.02 | 1.92 (0.96–3.82) | 0.06 |
ART-naïve before first visit | ||||
No | 1.00 | 1.00 | 1.00 | |
Yes | 0.65 (0.42–1.03) | 0.07 | 0.58 (0.34–0.99) | 0.05 |
CD4 count (cells/µL) | ||||
≤ 50 | 6.82 (3.62–12.85) | < 0.0001 | 2.45 (1.09–5.49) | 0.03 |
51–200 | 2.65 (1.31–5.37) | < 0.01 | 1.16 (0.51–2.67) | 0.72 |
201–350 | 1.54 (0.68–3.47) | 0.30 | 0.91 (0.35–2.35) | 0.85 |
> 350 | 1.00 | – | 1.00 | – |
Viral load | ||||
< 400 | 1.00 | – | – | – |
400 a 999 | 1.21 (0.37–3.99) | 0.76 | – | – |
≥ 1.000 | 0.82 (0.44–1.46) | 0.49 | – | – |
Prior AIDS-defining illness | ||||
No | 1.00 | – | 1.00 | – |
Yes | 5.03 (3.28–7.71) | < 0.0001 | 4.32 (2.33–8.00) | < 0.0001 |
INI cohort, 2004–2015 (N = 3747)