Table 5.
Treatment of ocular adnexal lymphomas by subtype and staging
| Treatment (n=82) Ann arbor stage | All subtypes total, n (%) | EMZL | FL low grade | FL high-grade | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
|
|
|||||||||||||||
| IE | IIE | IIIE | IVE | N/A | Total | IE | IIE | IIIE | IVE | Total | IE | IIE | IIIE | IVE | Total | ||
| EBRT | 38 (46) | 24 | 2 | 5 | 31 | 2 | 1 | 3 | 1 | 1 | |||||||
| Surgical excision with cryotherapy* | 14 (17) | 8 | 4 | 12 | 0 | ||||||||||||
| Biologics | 14 (17) | 6 | 3 | 1 | 10 | 1 | 1 | 1 | 3 | ||||||||
| ULDR | 4 (5) | 0 | 1 | 1 | 1 | 2 | 3 | ||||||||||
| Chemotherapy | 2 (2) | 1 | 1 | 0 | |||||||||||||
| EBRT+biologics | 5 (6) | 0 | 2 | 2 | 1 | 1 | 2 | ||||||||||
| Chemotherapy+biologic | 3 (4) | 1 | 1 | 1 | 1 | ||||||||||||
| EBRT+chemotherapy | 1 (1) | 1 | 1 | 0 | |||||||||||||
| Chemotherapy+BMT | 1 (1) | 0 | 0 | 0 | |||||||||||||
| 59 | 12 | ||||||||||||||||
*Surgical excision with cryotherapy as a sole treatment modality, followed by observation. EBRT=External beam radiation therapy; ULDR=Ultra-low-dose radiotherapy; BMT=Bone marrow transplant; EMZL=Extranodal marginal zone lymphoma; FL=Follicular lymphoma; N/A=Staging information not available; MCL=Mantle cell lymphoma; Extranodal marginal zone B-cell lymphoma" throughout