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. Author manuscript; available in PMC: 2022 May 18.
Published in final edited form as: Biochem Pharmacol. 2020 Oct 17;183:114291. doi: 10.1016/j.bcp.2020.114291

Fig. 1.

Fig. 1.

Sequence alignment of PnTx1, μ-KIIIA and the previously designed peptide Pn [24]. Key residues for NaV channel inhibition are shown in green [5,10,14,24] and cysteines are shown in blue. The asterisk indicates amidation. Orange lines (dashed and solid) signify disulfide bonds for KIIIA and Pn. Disulfide connectivity is not known for PnTx1. The sequence for PnTx1 continues after the … (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)