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. 2022 Apr 2;23(3):bbac092. doi: 10.1093/bib/bbac092

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© The Author(s) 2022. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Comparison of performance on G1 and G2 for scSNV genotype recovery, subclone assignment and tree reconstruction. (A) The violin plot of BiTSC with real segments as input, SCARLET with true CN tree and supported loss set as input, RobustClone, SCITE, BEAM and SiFit for error rate of recovered scSNV genotype matrix, ARI of subclone assignment and MP3 similarity on G1 dataset, where 0, 1 and 1 indicate best performance for error rate, ARI and MP3 similarity, respectively. (B) The violin plot of BiTSC with real segments as input, SCARLET with true CN tree and supported loss set as input, RobustClone, SCITE, BEAM and SiFit for error rate of recovered scSNV genotype matrix, ARI of subclone assignment and MP3 similarity on G2 dataset, where 0, 1 and 1 indicate best performance for error rate, ARI and MP3 distance, respectively.

Inline graphic — Comparison of performance on G1 and G2 for scSNV genotype recovery, subclone assignment and tree reconstruction. (A) The violin plot of BiTSC with real segments as input, SCARLET with true CN tree and supported loss set as input, RobustClone, SCITE, BEAM and SiFit for error rate of recovered scSNV genotype matrix, ARI of subclone assignment and MP3 similarity on G1 dataset, where 0, 1 and 1 indicate best performance for error rate, ARI and MP3 similarity, respectively. (B) The violin plot of BiTSC with real segments as input, SCARLET with true CN tree and supported loss set as input, RobustClone, SCITE, BEAM and SiFit for error rate of recovered scSNV genotype matrix, ARI of subclone assignment and MP3 similarity on G2 dataset, where 0, 1 and 1 indicate best performance for error rate, ARI and MP3 distance, respectively.