Table 2.

Tumor Response to Sotorasib Therapy According to Independent Central Review.^*

Variable	Patients (N = 124)
Objective response — % (95% CI)†	37.1 (28.6–46.2)
Disease control — % (95% CI)‡	80.6 (72.6–87.2)
Best response — no. (%)
Complete response	4 (3.2)
Partial response	42 (33.9)
Stable disease	54 (43.5)
Progressive disease	20 (16.1)
Could not be evaluated	2 (1.6)
Missing scan	2 (1.6)
Median duration of objective response (95% CI) — mo§	11.1 (6.9–NE)
Kaplan–Meier estimate of objective response (95% CI) — %
At 3 mo	90.5 (76.7–96.3)
At 6 mo	70.8 (54.3–82.2)
At 9 mo	57.3 (40.4–71.0)

^*NE denotes could not be evaluated.

^†Objective response was defined as a complete or partial response.

^‡Disease control was defined as a complete response, partial response, or stable disease.

^§The median duration of objective response was calculated on the basis of the 46 patients who had a complete or partial response.