Scheme 2. Investigation of the photochemistry of compounds with modifications to X, the NH group in the sulfonamide 1a. (A) General reaction scheme, and structures of derivatives. Isolated yields obtained by photosplicing are given in brackets. (B) Irradiation of 1c and detection of MeNH2 by GC-MS. (C) Irradiation of 1d and detection of TsNH2 by GC-MS. (D) Irradiation of 1h and detection of ethylene with 1H-NMR and HSQC experiments.
