Table 1.
Baseline characteristics between groups of NAFLD cases and controls
| Variables | Controls (n = 1,886) | NAFLD cases (n = 1,137) | p value |
|---|---|---|---|
| Age, years | 39.85±9.71 | 40.35±8.14 | 0.124b |
| Age n (%) | |||
| ≤40 years | 958 (50.8) | 597 (52.5) | 0.362a |
| >40 years | 928 (49.2) | 540 (47.5) | |
| Gender | |||
| Male | 1,567 (83.1) | 967 (85.0) | 0.156a |
| Female | 319 (16.9) | 170 (15.0) | |
| BMI, kg/m2 | 22.70±2.50 | 25.47±2.55 | <0.001b |
| Overweight, n (%) | |||
| No | 1,282 (71.7) | 309 (28.3) | <0.001a |
| Yes | 506 (28.3) | 783 (71.7) | |
| WC, cm | 81.40±7.96 | 88.95±7.98 | <0.001b |
| Abdominal obesity, n (%) | |||
| No | 1,559 (89.6) | 610 (57.1) | <0.001a |
| Yes | 181 (10.4) | 458 (42.9) | |
| SBP, mm Hg | 124.74±13.69 | 130.51±15.29 | <0.001b |
| DBP, mm Hg | 74.85±9.42 | 79.62±10.95 | <0.001b |
| Hypertension, n (%) | |||
| No | 1,151 (64.4) | 518 (47.5) | <0.001a |
| Yes | 635 (35.6) | 573 (52.5) | |
| TC, mmol/L | 4.51±0.81 | 4.77±0.90 | <0.001b |
| TG, mmol/L* | 1.03 (0.78, 1.34) | 1.66 (1.19, 2.29) | <0.001c |
| Hypertriglyceridemia, n (%) | |||
| No | 1,543 (86.5) | 582 (51.3) | <0.001a |
| Yes | 240 (13.5) | 553 (48.7) | |
| FPG, mmol/L* | 2.60 (2.31, 4.75) | 3.98 (2.37, 4.92) | <0.001c |
| Hyperglycemia, n (%) | |||
| No | 1,716 (96.2) | 1,043 (91.9) | <0.001a |
| Yes | 67 (3.8) | 92 (8.1) | |
| 25(OH)D3, ng/mL*d | 20.00 (16.84, 26.64) | 15.77 (11.93, 20.69) | <0.001c |
Overweight, BMI >24 kg/m2; abdominal obesity, WC >90 cm in males and >85 cm in females; hypertension, SBP/DBP ≥130/85 mm Hg; hypertriglyceridemia, serum triglyceride ≥1.7 mmol/L; hyperglycemia, FPG ≥5.6 mmol/L. NAFLD, nonalcoholic fatty liver disease; BMI, body mass index; WC, waist circumference; SBP, systolic blood pressure; DBP, diastolic blood pressure; TC, total cholesterol; TG, triacylglycerol; FPG, fasting plasma glucose. Results in bold type indicate statistically significant.
Non-normally distributed variables.
χ2 test.
Independent-samples t test.
Mann-Whitney U test.
Serum 25(OH)D3 levels were measured in 330 NAFLD cases and 317 controls.