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. 2022 May 18;17(5):e0268432. doi: 10.1371/journal.pone.0268432

Table 1. Baseline characteristics of COVID-19 patients who presented unfavorable outcomes (ventilation support need and death) and those who did not.

No VS VS p value Discharge Death p value
(n = 106) (n = 12) (n = 96) (n = 23)
Mean ± SD or % Mean ± SD or % Mean ± SD or % Mean ± SD or %
Males (%) 44.3 66.7 ns 44.8 52.2 ns
Age (y) 71.9 ± 14.6 64.8 ± 13.6 0.08 69.6 ± 14.4 77.5 ± 13.1 0.01
COMORBIDITIES
T2D (%) 21.7 0 nc 19.8 17.4 ns
Hypertension (%) 47.2 41.7 ns 46.9 47.8 ns
Underweight (%) 11.3 8.3 ns 6.3 27.2 0.005
Overweight (%) 31.8 25 ns 36.7 13.6 0.005
Obese (%) 17.1 25 ns 20.3 9.1 0.01
CVD (%) 29.3 41.7 ns 29.1 34.8 ns
Respiratory diseases (%) 14.1 0 nc 12.5 13.0 ns
CNS Disease (%) 16.0 0 nc 11.5 26.1 0.07
Malignancy (%) 23.6 25.0 ns 18.8 43.5 0.01
CKD (%) 12.8 8.3 ns 9.4 21.7 0.09
CONCOMITANT THERAPIES
Metformin (%) 13.9 0 nc 13.1 11.7 ns
Insulin (%) 1.1 0 nc 1.2 0 ns
Acetyilsalicylic acid (%) 32.3 25.0 ns 31.0 33.3 ns
Oral anticoagulants (%) 16.1 0 nc 14.3 16.7 ns
Beta-blockers (%) 26.9 28.6 ns 26.2 29.4 ns
ACEi/ARB (%) 34.4 42.9 ns 36.9 23.5 ns
Diuretics (%) 35.5 14.3 ns 33.3 35.3 ns
Statins (%) 25.8 28.6 ns 22.6 47.1 0.03

Abbreviations: ACEi, angiotensin converting enzyme inhibitor; ARB, angiotensin receptor blocker; CKD, chronic kidney disease; CNS, central nervous system; CVD, cardiovascular disease; ns, not significant; SD, standard deviation; T2D, type 2 diabetes; VS, ventilation support.