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. 2022 May 18;17(5):e0268432. doi: 10.1371/journal.pone.0268432

Table 3. Age- and gender-adjusted odds ratios of associations between comorbidities and ventilation support or in-hospital mortality.

VS (NIMV +/- IMV) In-hospital mortality
Comorbidities OR adj (95% CI) p value OR adj (95% CI) p value
T2D nc 0.8 (0.2–2.6) ns
Hypertension 1.0 (0.3–3.8) ns 0.7 (0.3–1.8) ns
Underweight 1.1 (0.1–10) ns 5.0 (1.2–20.8) 0.02
Overweight 0.7 (0.2–3.1) ns 0.3 (0.1–1.1) 0.07
Obesity 1.6 (0.3–6.9) ns 0.5 (0.1–2.4) ns
CVD 2.3 (0.6–8.9) ns 1.0 (0.4–2.7) ns
Respiratory diseases nc 0.9 (0.2–3.6) ns
CNS diseases nc 1.6 (0.45–5.7) ns
Malignancy 1.1 (0.3–4.7) ns 4.1 (1.5–11.8) 0.008
CKD 0.8 (0.1–7.3) ns 2.0 (0.6–7.0) ns

Abbreviations: CKD, chronic kidney disease; CNS, central nervous system; CVD, cardiovascular disease; IMV, invasive mechanical ventilation; nc, not calculable; NIMV, non-invasive mechanical ventilation; ns, not significant; T2D, type 2 diabetes; VS, ventilation support. ORadj, age- and gender-adjusted Odds Ratio; 95%CI, 95% Confidence Intervals.