Table 4. Age—and gender-adjusted odds ratios of significant associations between biochemical parameters assessed at day 1 and unfavorable outcomes (ventilation support and death).
| VS (NIMV +/- IMV) | In-hospital mortality | |||
|---|---|---|---|---|
| OR adj (95% CI) | p value | OR adj (95% CI) | p value | |
| Low Hb | 1.9 (0.4–9.2) | ns | 4.9 (1.4–17.6) | 0.02 |
| High WBC | 5.9 (1.0–32.7) | 0.04 | 7.1 (1.9–26.3) | 0.003 |
| High neutrophils | 3.1 (0.7–13.9) | ns | 21.5 (4.1–111.7) | 0.0001 |
| High BUN | 0.3 (0.03–2.7) | ns | 5.1 (1.6–16.5) | 0.007 |
| Low albumin | 1.3 (0.1–14.0) | ns | 5.7 (1.2–27.1) | 0.03 |
| Low total proteins | 12.0 (1.7–83.3) | 0.01 | 3.6 (1.1–11.6) | 0.03 |
| High IL-6 | 6.7 (0.8–57.4) | 0.08 | 1.6 (0.2–11.0) | ns |
| Low PaO 2 /FiO 2 | 2.3 (0.7–8.4) | ns | 2.4 (0.9–6.3) | ns |
Abbreviations: BUN, blood urea nitrogen; Hb, hemoglobin; IL-6, interleukin-6; IMV, invasive mechanical ventilation; NIMV, non-invasive mechanical ventilation; ns, not significant; VS, ventilation support; WBC, white blood cell. Low Hb if < 12 g/dL; High WBC > 10.8 x109/L; High neutrophils > 7.2 x109/L; High BUN > 55 mg/dL; Low albumin < 3 g/L; Low total proteins < 6 g/L; High IL-6 > 12.4 pg/mL; Low PaO2/FiO2 < 400. ORadj, age- and gender-adjusted Odds Ratio; 95%CI, 95% Confidence Intervals