Table 5. Significant age- and gender-adjusted associations of biochemical parameters assessed at day 7 with unfavorable outcomes (VS and death).
| VS (NIMV +/- IMV) | In-hospital mortality | |||
|---|---|---|---|---|
| OR adj (95% CI) | p value | OR adj (95% CI) | p value | |
| Low Hb | 1.5 (0.4–5.8) | ns | 3.6 (0.9–13.6) | 0.05 |
| High WBCs | 9.6 (1.6–57.0) | 0.01 | 5.6 (1.4–22.2) | 0.02 |
| High neutrophils | 11.5 (1.3–105.2) | 0.03 | 12.4 (1.5–101.5) | 0.02 |
| High BUN | 5.0 (1.0–24.4) | 0.04 | 4.2 (1.2–14.8) | 0.03 |
| Low albumin | 0.8 (0.1–4.5) | ns | 27.0 (4.8–151.0) | 0.0001 |
| Low PaO 2 /FiO 2 | 5.8 (1.3–25.6) | 0.02 | 1.0 (0.4–3.0) | ns |
Abbreviations: BUN, blood urea nitrogen; Hb, hemoglobin; IMV, invasive mechanical ventilation; nc, not calculable; NIMV, non-invasive mechanical ventilation; ns, not significant; VS, ventilation support; WBCs, white blood cells. Low Hb if < 12 g/dL; High WBC > 10.8 x109/L; High neutrophils > 7.2 x109/L; High BUN > 55 mg/dL; Low albumin < 3 g/L; Low PaO2/FiO2 < 400. ORadj, age- and gender-adjusted Odds Ratio; 95%CI, 95% Confidence Intervals.