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. 2022 May 18;17(5):e0268568. doi: 10.1371/journal.pone.0268568

Table 1. Clinical characteristics of patients in LP and SP groups.

Variables SP LP P value
Patients, n 34 31
Male sex, n (%) 18 (52.9) 14 (45.2) 0.622
Age, years 69.5 (57–78) 80 (63–85) 0.025 *
Height, cm 158.8 (151.7–166.4) 157 (147–162) 0.348
Body weight, kg 57.3 (48.4–65.6) 60.7 (50.1–75.5) 0.287
BMI, kg/m2 22.4 (20.2–25.3) 25.5 (22.2–29.5) 0.019 *
Plasma albumin, g/dl 4.0 (3.2–4.3) 3.2 (2.7–3.6) 0.002 *
ASA class (IQR) 2 (2 ‒ 2) 2 (2 ‒ 3) 0.061
Duration of surgery, min 146 (93–204) 118 (47–233) 0.393
Total duration of general anesthesia, min 193 (135–256) 169 (114–331) 0.932
Total dose of remimazolam administered, mg 75.4 (47.8–110.0) 67.1 (44.1–119.0) 0.958
Administration of flumazenil, n (%) 0 16 (51.6)

Data are median (IQR; 25% ‒ 75% interquartile range).

*significant difference.

SP, short period (time to extubation < 15 min); LP, long period (time to extubation ≥ 15 min); BMI, body mass index; ASA, American Society of Anesthesiologists.