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. 2022 May 18;17(5):e0268568. doi: 10.1371/journal.pone.0268568

Table 2. Predicted plasma concentration of remimazolam in LP and SP groups.

Variables SP LP P value
Patients, n 31 34
At the end of remimazolam infusion, μg/ml 0.278 (0.218–0.368) 0.277 (0.198–0.355) 0.371
At the time of extubation, μg/ml 0.146 (0.107–0.214) 0.101(0.070–0.139) 0.000 *

Data are median (IQR; 25% ‒ 75% interquartile range).

*significant difference.

SP, short period (time to extubation < 15 min); LP, long period (time to extubation ≥ 15 min).