Table 3. Log predicted remimazolam concentration in SP and LPF(-) groups.

Variables	SP	LPF(-)	P value
Patients, n	34	15
At the end of remimazolam infusion, log M	-6.33 (-6.44—-6.21)	-6.44 (-6.53—-6.30)	0.112
At the end of extubation, log M	-6.61 (-6.74—-6.45)	-6.85 (-6.95—-6.76)	0.000 *
Difference of concentration, log M	0.26 (0.21–0.33)	0.41 (0.33–0.47)	0.000 *

Data are median (IQR; 25% ‒ 75% interquartile range).

*significant difference.

SP, short period (time to extubation < 15 min); LPF(-), long period (time to extubation ≥ 15 min) without flumazenil.