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. 2022 May 18;269(9):4618–4622. doi: 10.1007/s00415-022-11188-7

Table 1.

Summary of aetiology-oriented laboratory studies

Blood and serum
 Anti-ds-DNA Negative
 ANA screening Negative
 Anti-MPO and anti-PR3 Negative
 Angiotensin converting enzyme 41 U/L (normal ≤ 51 U/L)
 Anti-AQ4 Negative
 Anti-contactin 1 Negative
 Anti-gangliosides (GD1a, GD1b, GM1, GQ1b) Negative
 Anti-MAG Negative
 Anti-MOG Negative
 Anti-neurofascin 140, 155, 186 Negative
 Anti-sulfatides Negative
 Erythrocyte sedimentation rate 10 mm/h
 Anti-SARS-CoV-2 (S1-RBD Ig) 863.0 U/mL
 HIV 1/2 Negative
 HSV 1 and 2 IgM and IgG negative
 VZV IgM negative; IgG positive
 CMV IgM negative; IgG positive
 EBV IgM negative; IgG positive
 HAV IgM and IgG negative
 anti-HBs Positive
 Anti-HCV Negative
 HEV IgM and IgG negative
 Borrelia burgdorferi IgM and IgG negative
 Interferon-gamma release assay Negative
 Treponema pallidum Non-reactive
Cerebrospinal fluid
 Cells 0,8 cells (Normal < 5 cells)
 Proteins 247.1 mg/dL (Normal < 45 mg/dL)
 Glucose 68 mg/dL
 Oligoclonal bands (OCB) Absent
 Cultures (bacterial) Negative
 Treponema pallidum (VDRL) Non-reactive
 Borrelia burgdorferi Negative
 Neurotropic viruses PCR array* Negative

ANA antinuclear antibodies, AQP4 Aquaporin-4, CMV cytomegalovirus, EBV Epstein–Barr virus, HAV Hepatitis A virus, HBs Hepatitis B surface antigen, HCV Hepatitis C virus, HEV Hepatitis E virus, HIV human immunodeficiency virus, HSV herpes simplex virus, MAG myelin associated glycoprotein, MOG myelin oligodendrocyte glycoprotein, PCR polymerase chain reaction, SARS-CoV-2 severe acute respiratory syndrome coronavirus 2, VZV varicella zoster virus

*HSV1, HSV2, CMV, EBV, HHV6, HHV7, VZV, adenovirus, enterovirus and parechovirus