Figure 1.

Effect of ethanol exposure on blood alcohol concentration (BAC) and S. pneumoniae burden in the lung. (A) Schematic diagram of ethanol exposure and S. pneumoniae infection. (B) Representative BAC measurements from serum at 30 minutes post-gavage. Each dot represents the value from a single animal from one experiment. The line for each group represents average value ± SEM. (C) Whole lungs were collected at 24 hours post-infection, homogenized, and plated on agar. S. pneumoniae colony forming units (CFU) were enumerated and data are presented as mean ± SEM. n = 4-6 mice per group per experiment and data are combined from 3 individual experiments. *p < 0.05 by unpaired t test.