Table 1.
General Characteristics of 1077 patient between AKI and Non-AKI group.
| Variables | Non-AKI (n=1017) | AKI (n=60) | Total (n=1077) | P-value | Missing |
|---|---|---|---|---|---|
| Age | 57.5±14.1 | 67.0±14.3 | 58.0±14.3 | <0.001 | 0 |
| Sex | |||||
| Female | 501/1017 (49.3%) | 14/60 (23.3%) | 515/1077 (47.8%) | <0.001 | 0 |
| Male | 516/1017 (50.7%) | 46/60 (76.7%) | 562/1077 (52.2%) | ||
| Hospitalization time (day) | 22.6±14.0 | 18.3±13.8 | 22.3±14.1 | 0.009 | 11 |
| Systolic BP (mm Hg) | 131.2±17.9 | 133.1±22.1 | 131.3±18.2 | 0.706 | 69 |
| Diastolic BP (mm Hg) | 81.7±12.8 | 79.0±12.8 | 81.5±12.8 | 0.179 | 72 |
| COVID-19 Severity | |||||
| Mild | 23/1017 (2.3%) | 0/60 (0%) | 23/1077 (2.1%) | <0.001 | 0 |
| Moderate | 553/1017 (54.4%) | 10/60 (16.7%) | 563/1077 (52.3%) | ||
| Severe | 342/1017 (33.6%) | 10/60 (16.7%) | 352/1077 (32.7%) | ||
| Critically severe | 99/1017 (9.7%) | 40/60 (66.7%) | 139/1077 (12.9%) | ||
| Basic illness | |||||
| Hypertension | 296/1017 (29.1%) | 21/60 (35.0%) | 317/1077 (29.4%) | 0.330 | 0 |
| Diabetes | 182/1017 (17.9%) | 18/60 (30.0%) | 200/1077 (18.6%) | 0.019 | 0 |
| CHD | 97/1017 (9.5%) | 8/60 (13.3%) | 105/1077 (9.7%) | 0.335 | 0 |
| COPD | 18/1017 (1.8%) | 5/60 (8.3%) | 23/1077 (2.1%) | 0.003 | 0 |
| CVD | 18/1017 (1.8%) | 4/60 (6.7%) | 22/1077 (2.0%) | 0.033 | 0 |
| Tumor | 37/1017 (3.6%) | 4/60 (6.7%) | 41/1077 (3.8%) | 0.399 | 0 |
| ICU admission | 35/1017 (3.4%) | 17/60 (28.3%) | 52/1077 (4.8%) | <0.001 | 0 |
| Death | 109/1017 (10.7%) | 39/60 (65%) | 148/1077 (13.7%) | <0.001 | 0 |
| Complications | |||||
| Respiratory failure | 101/1017 (9.9%) | 42/60 (70%) | 143/1077 (13.3%) | <0.001 | 0 |
| Gastrointestinal bleeding | 14/1017 (1.4%) | 8/60 (13.3%) | 22/1077 (2%) | <0.001 | 0 |
| Acute liver dysfunction | 318/1016 (31.3%) | 38/60 (63.3%) | 356/1076 (33.1%) | <0.001 | 1 |
| Acute myocardial injury | 49/1014 (4.8%) | 32/59 (54.2%) | 81/1073 (7.5%) | <0.001 | 4 |
| Heart failure | 34/1017 (3.3%) | 23/60 (38.3%) | 57/1077 (5.3%) | <0.001 | 0 |
| ARDS | 54/1016 (5.3%) | 30/60 (50%) | 84/1076 (7.8%) | <0.001 | 1 |
| Cerebrovascular accident | 9/1016 (0.9%) | 4/60 (6.7%) | 13/1076 (1.2%) | 0.004 | 1 |
| Bacteremia | 15/1017 (1.5%) | 6/60 (10%) | 21/1077 (1.9%) | <0.001 | 0 |
| DIC | 9/1016 (0.9%) | 11/60 (18.3%) | 20/1076 (1.9%) | <0.001 | 1 |
| CKD | 83/1017 (8.2%) | 18/60 (30.0%) | 101/1077 (9.4%) | <0.001 | 0 |
| hematuria | 77/235 (32.8%) | 18/27 (66.7%) | 95/262 (36.3%) | 0.001 | 815 |
| proteinuria | 27/232 (11.6%) | 14/26 (53.8%) | 41/258 (15.9%) | <0.001 | 819 |
| ACEI/ARB history | 45/742 (6.1%) | 2/46 (4.3%) | 47/788 (6.0%) | 0.876 | 289 |
BP, blood pressure; CKD, Chronic kidney disease; CHD, coronary heart disease; COPD, Chronic obstructive pulmonary disease; AKI, acute kidney injury; CVD, cerebrovascular disease; ARDS, Acute Respiratory Distress Syndrome; DIC, disseminated intravascular coagulation; LDH, Lactate dehydrogenase; UA, uric acid; PCT, Procalcitonin; SO2, Blood oxygen saturation; PLT, Blood platelets; CRP, C-reactive protein.