Table 5.
The results of multivariate cox regression model among patients with different AKI and CKD status.
| Variables | Level | Pool estimates based on imputed datasets (n=1066) | Estimates based on complete dataset (n=507) |
||||||
|---|---|---|---|---|---|---|---|---|---|
| HR | 95%CI | p | HR | 95%CI | p | ||||
| Lower | Upper | Lower | Upper | ||||||
| Non-AKI/CKD | Ref | Ref | |||||||
| AKI only | 3.39 | 2.06 | 5.57 | <0.001 | 4.04 | 2.17 | 7.53 | <0.001 | |
| CKD only | 1.28 | 0.71 | 2.30 | 0.411 | 1.50 | 0.63 | 3.56 | 0.355 | |
| AKI/CKD | 4.20 | 2.19 | 8.06 | <0.001 | 6.15 | 2.76 | 13.73 | <0.001 | |
| Sex | Female | Ref | Ref | ||||||
| Male | 1.10 | 0.76 | 1.60 | 0.619 | 1.21 | 0.68 | 2.16 | 0.518 | |
| Age | 1.00 | 0.99 | 1.02 | 0.552 | 1.00 | 0.98 | 1.02 | 0.802 | |
| COVID-19 severity | Mild or Moderate | Ref | Ref | ||||||
| Severe or critically severe | 2.43 | 1.46 | 4.03 | <0.001 | 3.55 | 1.36 | 9.29 | 0.010 | |
| Basic illness | No | Ref | Ref | ||||||
| Yes | 0.94 | 0.65 | 1.34 | 0.718 | 1.22 | 0.72 | 2.06 | 0.461 | |
| Lymphocyte count | 0.74 | 0.50 | 1.09 | 0.129 | 0.62 | 0.34 | 1.16 | 0.135 | |
| CRP | 1.01 | 1.00 | 1.01 | <0.001 | 1.01 | 1.01 | 1.02 | <0.001 | |
| LDH | 1.00 | 1.00 | 1.00 | 0.016 | 1.00 | 1.00 | 1.00 | 0.178 | |
| D-dimer | 1.06 | 0.99 | 1.13 | 0.092 | 1.08 | 0.99 | 1.17 | 0.088 | |
| HsTnI | 1.00 | 1.00 | 1.00 | 0.769 | 1.00 | 1.00 | 1.00 | 0.174 | |
Note: Basic illness yes means the patient has one or more of the following basic illnesses: Hypertension, Diabetes, CHD, COPD, CVD, Tumor.