Table 6.
The results of multivariate cox regression model between AKI and Non-AKI groups.
| Variables | Level | Pool estimates based on imputed datasets (n=1066) | Estimates based on complete dataset (n=507) | ||||||
|---|---|---|---|---|---|---|---|---|---|
| HR | 95%CI | p | HR | 95%CI | p | ||||
| Lower | Upper | Lower | Upper | ||||||
| AKI | No | Ref | Ref | ||||||
| Yes | 3.44 | 2.26 | 5.24 | <0.001 | 4.15 | 2.45 | 7.01 | <0.001 | |
| Sex | Female | Ref | Ref | ||||||
| Male | 1.12 | 0.77 | 1.62 | 0.559 | 1.28 | 0.73 | 2.27 | 0389 | |
| Age | 1.00 | 0.99 | 1.02 | 0.556 | 1.00 | 0.98 | 1.02 | 0.866 | |
| COVID-19 severity | Mild or Moderate | Ref | Ref | ||||||
| Severe or critically severe | 2.41 | 1.45 | 4.00 | 0.001 | 3.44 | 1.32 | 8.97 | 0.012 | |
| Basic illness | No | Ref | Ref | ||||||
| Yes | 0.96 | 0.68 | 1.37 | 0.833 | 1.28 | 0.76 | 2.14 | 0.357 | |
| lymphocyte count | 0.74 | 0.50 | 1.10 | 0.139 | 0.66 | 0.36 | 1.21 | 0.180 | |
| CRP | 1.01 | 1.00 | 1.01 | <0.001 | 1.01 | 1.01 | 1.02 | <0.001 | |
| LDH | 1.00 | 1.00 | 1.00 | 0.003 | 1.00 | 1.00 | 1.00 | 0.049 | |
| D-dimer | 1.06 | 0.99 | 1.13 | 0.085 | 1.08 | 1.00 | 1.18 | 0.063 | |
| HsTnI | 1.00 | 1.00 | 1.00 | 0.873 | 1.00 | 1.00 | 1.00 | 0.265 | |
Note: Basic illness yes means the patient has one or more of the following basic illnesses: Hypertension, Diabetes, CHD, COPD, CVD, Tumor.