Table 8.
General characteristics of 1077 patients with different AKI and CKD status.
| Variables | Non-CKD (n=976) | CKD (n=101) | Total (n=1077) | P-value | Missing | ||
|---|---|---|---|---|---|---|---|
| Non-AKI (n=934) | AKI (n=42) | Non-AKI (n=83) | AKI (n=18) | ||||
| age | 56.9±14.1 | 67.1±13.3 | 63.8±12.1 | 66.6±16.8 | 58.0±14.3 | <0.001 | 0 |
| Gender | <0.001 | 0 | |||||
| Female | 469/934 (50.2%) | 10/42 (23.8%) | 32/83 (38.6%) | 4/18 (22.2%) | 515/1077 (47.8%) | ||
| Male | 465/934 (49.8%) | 32/42 (76.2%) | 51/83 (61.4%) | 14/18 (77.8%) | 562/1077 (52.2%) | ||
| Hospitalization time (day) | 22.4±13.8 | 18.9±14.2 | 24.8±16.7 | 16.9±13.1 | 22.3±14.1 | 0.050 | 11 |
| Systolic BP (mm Hg) | 130.9±17.5 | 132.9±21.6 | 134.7±21.7 | 133.7±23.9 | 131.4±18.2 | 0.297 | 69 |
| Diastolic BP (mm Hg) | 81.8±12.5 | 78.9±11.0 | 80.7±16.3 | 79.2±16.9 | 81.5±12.8 | 0.549 | 72 |
| Basic illness | |||||||
| Hypertension | 243/934 (26%) | 10/42 (23.8%) | 53/83 (63.9%) | 11/18 (61.1%) | 317/1077 (29.4%) | <0.001 | 0 |
| Diabetes | 151/934 (16.2%) | 9/42 (21.4%) | 31/83 (37.3%) | 9/18 (50%) | 200/1077 (18.6%) | <0.001 | 0 |
| CHD | 84/934 (9%) | 7/42 (16.7%) | 13/83 (15.7%) | 1/18 (5.6%) | 105/1077 (9.7%) | 0.085 | 0 |
| COPD | 16/934 (1.7%) | 5/42 (11.9%) | 2/83 (2.4%) | 0/18 (0%) | 23/1077 (2.1%) | 0.005 | 0 |
| Cerebrovascular disease | 14/934 (1.5%) | 2/42 (4.8%) | 4/83 (4.8%) | 2/18 (11.1%) | 22/1077 (2%) | 0.005 | 0 |
| Tumor | 34/934 (3.6%) | 3/42 (7.1%) | 3/83 (3.6%) | 1/18 (5.6%) | 41/1077 (3.8%) | 0.418 | 0 |
| Transferred to ICU | 24/934 (2.6%) | 12/42 (28.6%) | 11/83 (13.3%) | 5/18 (27.8%) | 52/1077 (4.8%) | <0.001 | 0 |
| Death | 90/934 (9.6%) | 24/42 (57.1%) | 19/83 (22.9%) | 15/18 (83.3%) | 148/1077 (13.7%) | <0.001 | 0 |
| Complications | |||||||
| Respiratory failure | 81/934 (8.7%) | 25/42 (59.5%) | 20/83 (24.1%) | 17/18 (94.4%) | 143/1077 (13.3%) | <0.001 | 0 |
| Gastrointestinal bleeding | 10/934 (1.1%) | 3/42 (7.1%) | 4/83 (4.8%) | 5/18 (27.8%) | 22/1077 (2%) | <0.001 | 0 |
| Acute liver dysfunction | 284/933 (30.4%) | 23/42 (54.8%) | 34/83 (41%) | 15/18 (83.3%) | 356/1076 (33.1%) | <0.001 | 1 |
| Acute myocardial injury | 38/931 (4.1%) | 21/42 (50%) | 11/83 (13.3%) | 11/17 (64.7%) | 81/1073 (7.5%) | <0.001 | 4 |
| Heart failure | 28/934 (3%) | 10/42 (23.8%) | 6/83 (7.2%) | 13/18 (72.2%) | 57/1077 (5.3%) | <0.001 | 0 |
| ARDS | 42/933 (4.5%) | 14/42 (33.3%) | 12/83 (14.5%) | 16/18 (88.9%) | 84/1076 (7.8%) | <0.001 | 1 |
| Cerebrovascular accident | 8/933 (0.9%) | 3/42 (7.1%) | 1/83 (1.2%) | 1/18 (5.6%) | 13/1076 (1.2%) | 0.008 | 1 |
| Bacteremia | 10/934 (1.1%) | 3/42 (7.1%) | 5/83 (6%) | 3/18 (16.7%) | 21/1077 (1.9%) | <0.001 | 0 |
| DIC | 6/933 (0.6%) | 4/42 (9.5%) | 3/83 (3.6%) | 7/18 (38.9%) | 20/1076 (1.9%) | <0.001 | 1 |
| hematuria | 39/178 (21.9%) | 8/15 (53.3%) | 38/57 (66.7%) | 10/12 (83.3%) | 95/262 (36.3%) | <0.001 | 815 |
| proteinuria | 5/177 (2.8%) | 5/15 (33.3%) | 22/55 (40%) | 9/11 (81.8%) | 41/258 (15.9%) | <0.001 | 819 |
| ACEI/ARB history | 37/677 (5.5%) | 0/33 (0%) | 8/65 (12.3%) | 2/13 (15.4%) | 47/788 (6%) | 0.024 | 289 |
BP, blood pressure; Admission to outcome(day): Refers to the time from hospital admission to cure discharge or died. CKD, Chronic kidney disease; CHD, coronary heart disease; COPD, Chronic obstructive pulmonary disease; AKI, acute kidney injury; CVD, cerebrovascular disease; ARDS, Acute Respiratory Distress Syndrome; DIC, disseminated intravascular coagulation; LDH, Lactate dehydrogenase; UA, uric acid; PCT, Procalcitonin; SO2, Blood oxygen saturation; PLT, Blood platelets; CRP, C-reactive protein.