Supplementary Table 2.
HRs and 95% CIs for Associations Between Metabolic Syndrome Components and Pancreatic Cancer Risk by Sex
| Metabolic syndrome component | HR (95% CI)a,b |
|
|---|---|---|
| Women | Men | |
| Obesity (IDF 2005 definition) | 1.63 (1.21–2.19) | 1.21 (0.92–1.58) |
| Obesity (NCEP-ATPIII definition) | 1.38 (1.04–1.83) | 1.30 (1.01–1.69) |
| HDL cholesterol | 1.45 (1.09–1.93) | 1.08 (0.83–1.41) |
| Abnormal glucose metabolism | 1.82 (1.35–2.44) | 1.61 (1.23–2.09) |
| Hypertension | 1.44 (1.09–1.91) | 0.99 (0.76–1.28) |
| High triglycerides | 1.13 (0.85–1.50) | 1.00 (0.78–1.28) |
NOTE: Boldface indicates statistical significance.
CI, Confidence interval; HR, hazard ratio; IDF 2005, International Diabetes Federation 2005; NCEP-ATPIII, National Cholesterol Education Program – Adult Treatment Panel III.
Multivariable models were adjusted for total physical activity (<10, 10–20, 20–40, 40–60, >60 MET hour/week), height (cm, continuous), alcohol consumption frequency (never, special occasions only, 1–3 times/month, 1–2 times per week, 3–4 times/week, daily or almost daily, unknown/prefer not to answer), smoking intensity (never, previous, current <15 per day, current ≥15 per day, current unknown intensity, unknown/prefer not to answer), frequency of red and processed meat consumption (<2 per week, 2–2.99 times/week, 3–3.99 times/week, ≥4/week, unknown), educational level (CSE/GCSE/O-level, NVQ/HND/A-level/AS-level, other professional qualification, college/university degree, missing/prefer not to answer), regular aspirin or ibuprofen use (yes/no), ever use of hormone replacement therapy (yes/no) and, where appropriate, fasting time (hours, continuous).
HRs are given for the presence compared with the absence of each component.