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. 2022 Apr 18;28(5):1006–1013. doi: 10.1038/s41591-022-01767-6

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© This is a U.S. government work and not under copyright protection in the U.S.; foreign copyright protection may apply 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Extended Data Fig. 6 — Plots show log(odds) of each of six diseases versus quantile (n = 10) of standardized population structure-adjusted PRS (PRS_std-adj) among up to 786 MGBB participants of reported Asian race. Results not reported for CRCa, PrCa, or AFib due to 0 cases in at least one quantile. The correlation coefficient, r, is shown in each panel. Abbreviations: AFib, atrial fibrillation; BrCa, breast cancer; CAD, coronary artery disease; CRCa, colorectal cancer; MGBB, Mass General Brigham Biobank; OR, odds ratio; PrCa, prostate cancer; PRS, polygenic risk score; T2D, type 2 diabetes.