Extended Data Fig. 4. Mutational spectra for the DNMs hypermutated individuals part 2.

(a–f correspond to individual GEL_6, GEL_7, GEL_8, GEL_9, GEL_10 and GEL_11 respectively). Each row is a hypermutated individual showing the mutational spectra according to count of mutations per each single base change (with CpG>TpG mutations separated from other C>T mutations) and the second plot is the mutation count for all 96 mutations in their trinucleotide context. The x-axis demonstrates the reference trinucleotide sequence with the mutated base highlighted. The colour and label on the bar above indicates the mutation type.