Table 4.
Summary of the case reports/case series findings.
| Overall | ||||
|---|---|---|---|---|
| Types of study | Number of studies | Total patients with COVID-19 | Total patients with COVID-19 and HIV | n/Na (%) |
| Case report | 33 | 36 | 36 | 36/36 (100.0) |
| Case series | 20 | 77 | 75 | 75/77 (97.4) |
| Variables | Number of studies | Number of patients with COVID-19 and HIV | n/Na (%) | |
|---|---|---|---|---|
| Underlying disease | Metabolic syndrome | 1 | 1 | 1/111 (0.9) |
| Dementia | 1 | 1 | 1/111 (0.9) | |
| Cancer | 4 | 4 | 4/111 (3.6) | |
| CVAb | 2 | 2 | 2/111 (1.8) | |
| COPDc | 4 | 7 | 7/111 (6.3) | |
| Obesity | 7 | 9 | 9/111 (8.1) | |
| Renal disease | 4 | 4 | 4/111 (3.6) | |
| Hyperlipidemia | 3 | 3 | 3/111 (2.7) | |
| Asthma | 1 | 1 | 1/111 (0.9) | |
| Hypertension | 18 | 30 | 30/111 (27) | |
| Obstructive sleep apnea | 1 | 1 | 1/111 (0.9) | |
| Coronary heart disease | 9 | 12 | 12/111 (10.8) | |
| Diabetes | 12 | 18 | 18/111 (16.2) | |
| Liver disease | 1 | 1 | 1/111 (0.9) | |
| Pulmonary disease | 5 | 11 | 11/111 (9.9) | |
| Clinical manifestation | Cough | 34 | 56 | 56/111 (50.4) |
| Diarrhea | 11 | 11 | 11/111 (9.9) | |
| Skin lesion | 2 | 2 | 2/111 (1.8) | |
| Hypoventilation | 1 | 1 | 1/111 (0.9) | |
| Fatigue | 8 | 8 | 8/111 (7.2) | |
| Myalgia | 9 | 9 | 9/111 (8.1) | |
| Poor appetite | 3 | 3 | 3/111 (2.7) | |
| Fever | 41 | 66 | 66/111 (59.4) | |
| Blood pressure | 5 | 7 | 7/111 (6.3) | |
| Anorexia | 4 | 4 | 4/111 (3.6) | |
| Headache | 7 | 9 | 9/111 (8.1) | |
| Hypoxemia | 4 | 4 | 4/111 (3.6) | |
| Malaise | 2 | 2 | 2/111 (1.8) | |
| Weight loos | 1 | 1 | 1/111 (0.9) | |
| Dysphagia | 1 | 1 | 1/111 (0.9) | |
| Dyspnoea | 30 | 50 | 50/111 (45.0) | |
| Nausea | 2 | 2 | 2/111 (1.8) | |
| Adynamia | 1 | 2 | 2/111 (1.8) | |
| Hyposmia | 1 | 1 | 1/111 (0.9) | |
| Sore throat | 8 | 8 | 8/111 (7.2) | |
| Asthenia | 2 | 5 | 5/111 (4.5) | |
| Weakness | 6 | 6 | 6/111 (5.4) | |
| Muscle aches | 1 | 1 | 1/111 (0.9) | |
| Chills | 1 | 1 | 1/111 (0.9) | |
| Chest pain | 10 | 10 | 10/111 (9.0) | |
| Tachycardia | 2 | 3 | 3/111 (2.7) | |
| Abdominal pain | 5 | 5 | 5/111 (4.5) | |
| Encephalopathy | 1 | 1 | 1/111 (0.9) | |
| Rhinorrhea | 1 | 1 | 1/111 (0.9) | |
| Wheezing | 1 | 1 | 1/111 (0.9) | |
| Dizziness | 2 | 2 | 2/111 (1.8) | |
| Confusion | 3 | 3 | 3/111 (2.7) | |
| Vomiting | 2 | 2 | 2/111 (1.8) | |
| Hypogeusia | 1 | 1 | 1/111 (0.9) | |
| Seizure | 1 | 1 | 1/111 (0.9) | |
| Pharyngitis | 1 | 2 | 2/111 (1.8) | |
| Concurrent infection | Hepatitis C virus | 6 | 12 | 12/111 (10.8) |
| M. tuberculosis | 5 | 7 | 7/111 (6.3) | |
| Histoplasma capsulatum | 1 | 1 | 1/111 (0.9) | |
| Hepatitis B virus | 3 | 3 | 3/111 (2.7) | |
| Herpes simplex virus | 1 | 1 | 1/111 (0.9) | |
| T. pallidum | 2 | 4 | 4/111 (3.6) | |
| S. pneumoniae | 1 | 1 | 1/111 (0.9) | |
| Influenza A virus | 1 | 1 | 1/111 (0.9) | |
| P. jirovecii | 4 | 4 | 4/111 (3.6) | |
| C. albicans | 3 | 3 | 3/111 (2.7) | |
| C. neoformans | 2 | 2 | 2/111 (1.8) | |
| CT Scan findings | Ground-glass opacification | 24 | 35 | 35/111 (31.5) |
| Bilateral abnormalities | 15 | 18 | 18/111 (16.2) | |
| Large cavitation | 1 | 1 | 1/111 (0.9) | |
| Pleural empyema | 3 | 3 | 3/111 (2.7) | |
| Reticular interstitial thickening | 1 | 3 | 3/111 (2.7) | |
| High-density patchy | 3 | 3 | 3/111 (2.7) | |
| Atypical bilateral pneumonia | 12 | 16 | 16/111 (14.4) | |
| Interstitial infiltrate | 2 | 3 | 3/111 (2.7) | |
| Normal | 4 | 9 | 9/111 (8.1) | |
| Laboratory findings | Lymphocytopenia | 20 | 33 | 33/111 (29.7) |
| Leukopenia | 6 | 7 | 7/111 (6.3) | |
| Thrombocytopenia | 3 | 3 | 3/111 (2.7) | |
| Elevated CRPd | 30 | 49 | 49/111 (44.1) | |
| Elevated platelet | 1 | 1 | 1/111 (0.9) | |
| Elevated IL-6 | 5 | 12 | 12/111 (10.8) | |
| Neutrophilia | 3 | 3 | 3/111 (2.7) | |
| High lymphocyte | 6 | 8 | 8/111 (7.2) | |
| High ferritin | 9 | 19 | 19/111 (17.1) | |
| High ESRe | 1 | 1 | 1/111 (0.9) | |
| High WBC | 7 | 9 | 9/111 (8.1) | |
| High LDHf | 16 | 27 | 27/111 (24.3) | |
| Increased ASTg | 7 | 12 | 12/111 (10.8) | |
| Increased ALTh | 7 | 11 | 11/111 (9.9) | |
| D-dimer elevated | 11 | 18 | 18/111 (16.2) | |
| Anemia | 1 | 2 | 2/111 (1.8) | |
| High CD4 | 4 | 5 | 5/111 (4.5) | |
| Low CD4 | 25 | 43 | 43/111 (38.7) | |
| Detection methods | Serology | 21 | 45 | 45/111 (40.5) |
| Real-time PCR | 42 | 85 | 85/111 (76.5) | |
| CTi Scan | 35 | 70 | 70/111 (63.0) | |
| CXRj | 10 | 35 | 35/111 (31.5) | |
| PCRk | 11 | 24 | 24/111 (21.6) | |
| Gender | Male | 46 | 86 | 86/111 (77.4) |
| Female | 13 | 18 | 18/111 (16.2) | |
| TSFl | 3 | 4 | 4/111 (3.6) | |
| Outcome | Live | 41 | 83 | 83/111 (74.7) |
| Death | 10 | 19 | 19/111 (17.1) |
a
n, number of patients with any variables; N, the total number of patients with COVID-19, nr; not reported.
b
Cerebrovascular accident.
c
Chronic obstructive pulmonary disease.
d
C-reactive protein.
e
Erythrocyte sedimentation rate.
f
Lactate dehydrogenase.
g
Aspartate aminotransferase.
h
Alanine aminotransferase.
i
Computerized tomography.
j
Chest X-rays.
k
Polymerase chain reaction.
l
Trans female.