Table 6.
Top items of enrichment analysis of genes in five modules.
| Module | ONTOLOGY | ID | Description | P value | P.adjust | geneID | Count |
|---|---|---|---|---|---|---|---|
| 1 | BP | GO:0050657 | Nucleic acid transport | 1.74E-07 | 1.43E-05 | EIF4E/XPO1/YBX1/NPM1 | 4 |
| 1 | KEGG | hsa03013 | Nucleocytoplasmic transport | 1.04E-03 | 1.56E-02 | EEF1A1/XPO1 | 2 |
| 2 | BP | GO:0060337 | Type I interferon signaling pathway | 2.91E-12 | 2.43E-10 | EGR1/IFITM2/IRF8/IFITM1/ISG20 | 5 |
| 2 | KEGG | hsa05133 | Pertussis | 2.79E-02 | 6.19E-02 | IRF8 | 1 |
| 3 | BP | GO:0043062 | Extracellular structure organization | 1.88E-07 | 3.44E-05 | THBS1/ITGB1/FN1/CD47 | 4 |
| 3 | KEGG | hsa04512 | ECM-receptor interaction | 1.30E-08 | 4.02E-07 | THBS1/ITGB1/FN1/CD47 | 4 |
| 4 | BP | GO:0000209 | Protein polyubiquitination | 5.65E-06 | 4.40E-04 | UBE2D3/UBA52/RNF146 | 3 |
| 4 | KEGG | hsa04120 | Ubiquitin mediated proteolysis | 3.05 E−04 | 2.74E-03 | UBE2D3/UBA52 | 2 |
| 5 | BP | GO:0048207 | Vesicle targeting, rough ER to cis-Golgi | 4.09E-08 | 9.04E-07 | SEC23A/MCFD2/CTSC | 3 |
| 5 | KEGG | hsa04210 | Apoptosis | 3.33E-05 | 4.17E-02 | CTSC | 1 |
BP: biological process; KEGG: Kyoto Encyclopedia of Genes and Genomes.