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. 2022 May 18;12:8316. doi: 10.1038/s41598-022-11904-3

Table 5.

The IC50 value of Pt(TSC)Cl complex and cisplatin on cancer and normal cell lines.

IC50 (µM)
Cell lines 24 h 48 h 72 h
Cis Pt(TSC)Cl complex P value Cis Pt(TSC)Cl complex P value Cis Pt(TSC)CI complex P value
A549 96.8 146.6 42.93 101.7 13.12 69.28
MCF-7 162 200 142 193 150 181
Caco-2 149 17.2  < 0.00001 107 2.3  < 0.00001 37.32 1.75  < 0.00001
Hek293 4.15 63.9  < 0.00001

*Cis: Cisplatin, A549: Human lung cancer cells, Caco-2: Human colon cancer cells, MCF-7 Human breast cancer cells and Hek293: Human embryonic kidney cells.