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. 2022 May 18;12:8316. doi: 10.1038/s41598-022-11904-3

Table 6.

Quantitative results of Cell cycle distribution of MCF-7, A549 and Caco-2 cells treated with the indicated IC50 concentrations of cisplatin and Pt(TSC)Cl complex for 48 h determined by staining the DNA content of the cell followed by flow cytometry. The percentage of cells in G0/G1, S or G2/M phase is indicated.

A549 MCF-7 Caco-2
Control Cis Pt(TSC)Cl
complex
Control Cis Pt(TSC)Cl
complex
Control Cis Pt(TSC)Cl
complex
SubG1 0.32 0.42 21.78 0.14 6.8 4.95 4.55 10.28 50.82
G0/G1 66.38 66.94 47.71 67.38 37.21 53.17 54.68 41.73 30.34
S 14.56 16.13 13.94 16.85 37.43 27.72 19.90 19.61 14.91
G2/M 17.72 16.08 15.66 15.73 15.88 14.70 21.45 27.13 5.08

*Cis: Cisplatin, A549: Human lung cancer cells, Caco-2: Human colon cancer cells, MCF-7 Human breast cancer cells.