Table 2.

Clinical variables across levels of treatment intensity

Prophylaxis only vs. Low intensity treatment
	Prophylaxis only N=54	Low intensity treatment N=23	P value
Age	57[49–68]	65 [50–78]	0.109
CCI	2 [1–3]	3 [1–4]	0.140
Fisher Score			0.225
1	0 (0%)	0 (0%)
2	6 (11%)	0 (0%)
3	42 (78%)	19 (83%)
4	6 (11%)	4 (17%)
Fresh Score	3 [2–4]	5[4–6]	0.008
First 24-hr epileptiform activity burden			0.078
None	46 (85%)	15 (65%)
Rare	5 (9%)	2 (9%)
Occasional	1 (2%)	2 (9%)
Frequent	0 (0%)	0 (0%)
Abundant	2 (4%)	3 (13%)
Continuous	0 (0%)	1 (4%)
Prophylaxis only vs. High intensity treatment
	Prophylaxis only N=54	High intensity treatment N=17
Age	57[49–68]	59 [51–64]	0.909
CCI	2 [1–3]	2 [1–2]	0.654
Fisher Score			0.163
1	0 (0%)	0 (0%)
2	6 (11%)	2 (12%)
3	42 (78%)	10 (56%)
4	6 (11%)	5 (29%)
Fresh Score	3 [2–4]	4[4–6]	0.043
First 24-hr epileptiform activity burden
None	46 (85%)	5 (29%)	<0.001
Rare	5 (9%)	1 (6%)
Occasional	1 (2%)	2 (12%)
Frequent	0 (0%)	3 (18%)
Abundant	2 (4%)	6 (35%)
Continuous	0 (0%)	0 (0%)
Low intensity vs. High intensity treatment
	Low intensity treatment N=23	High intensity treatment N=17	p-value
Age	65 [50–78]	59 [51–64]	0.191
CCI	3 [1–4]	2 [1–2]	0.072
Fisher Score			0.119
1	0 (0%)	0 (0%)
2	0 (0%)	2 (12%)
3	19 (83%)	10 (56%)
4	4 (17%)	5 (29%)
Fresh Score	5[4–6]	4[4–6]	0.528
First 24-hr epileptiform activity burden			0.053
None	15 (65%)	5 (29%)
Rare	2 (9%)	1 (6%)
Occasional	2 (9%)	2 (12%)
Frequent	0 (0%)	3 (18%)
Abundant	3 (13%)	6 (35%)
Continuous	1 (4%)	0 (0%)

CCI: Charlson Comorbidity index