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. Author manuscript; available in PMC: 2022 Nov 5.
Published in final edited form as: Nat Genet. 2022 May 5;54(5):573–580. doi: 10.1038/s41588-022-01054-7

Extended Data Fig. 9. Trace plots and autocorrelation functions (ACFs) for assessing the convergence and mixing of the Gibbs sampler used in PRS-CSx.

Extended Data Fig. 9

Left panels: Trace plots, after discarding the burn-in iterations and thinning the Markov chain by a factor of 5, for the posterior effects of rs7412 on low-density lipoprotein cholesterol when integrating UKBB, BBJ and PAGE GWAS summary statistics using PRS-CSx. Right panels: The autocorrelation functions (ACFs) for the traces shown on the left.