TABLE 1.
Clinical and demographic characteristics of 228 patients from five studies included in the systematic review
| Reference (study) | Research type | Patient No | Country | Language | Interventions | Outcome measures |
|---|---|---|---|---|---|---|
| Zhang Liantao (2019) | RCTs | 90 | China | English | FTY720 ST | ④⑦ |
| De‐Cai Tian (2018) | RCTs | 46 | China | English | FTY720 ST | ①② |
| Zilong Zhu (2015) | RCTs | 47 | China | English | FTY720 ST | ①②⑤ |
| Ying Fu (2014) | RCTs | 22 | China | English | FTY720 ST | ①③④⑥ |
| De‐Cai Tian (2017) | RCTs | 23 | China | Chinese | FTY720 ST | ①②③⑤⑥ |
RCTs: randomized clinical trials, FTY720:fingolimod, ST: standardized treatment, ① the proportion of patients whose MRS score was 0,1 at day 90, ② the change of NIHSS scores over 24 h, ③ the change of NIHSS scores at day 7, ④ the change of NIHSS scores at day 90, ⑤ relative infarct lesion growth over 24 h, ⑥ relative infarct lesion growth at day 7, ⑦ the mean difference in the change in MRS score at day 90.